dcc sirnas Search Results


dcc sirna  (OriGene)
90
OriGene dcc sirna
The effects of silencing of endogenous Netrin‐1 ( NTN ‐1) by NTN ‐1 <t>small</t> <t>interfering</t> <t>RNA</t> (si RNA ) on blood‐brain barrier integrity at 24 hours after subarachnoid hemorrhage ( SAH ). NTN ‐1 si RNA aggravated neurological deficits (A) and increased brain water content (B) and Evans blue ( EB ) extravasation (C) in both hemispheres. n=6 for each group. D, Representative fluorescent micrograph of EB extravasation and quantitative analyses of the intensity of EB fluorescence in the ipsilateral cortex. n=2 for each group. * P <0.05 vs sham, # P <0.05 vs Vehicle, & P <0.05 vs NTN ‐1 and Scr si RNA ; @ P <0.05 vs NTN ‐1. LH indicates left hemisphere; RH , right hemisphere; Scr si RNA , scramble si RNA . Scale bar=25 μm.
Dcc Sirna, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dcc+sirnas/Dcc+Rat+siRNA+Oligo+Duplex/pmc05524080-48-12-14
Average 90 stars, based on 1 article reviews
dcc sirna - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
dcc sirnas  (Santa Cruz Biotechnology)
90
Santa Cruz Biotechnology dcc sirnas
The effects of silencing of endogenous Netrin‐1 ( NTN ‐1) by NTN ‐1 <t>small</t> <t>interfering</t> <t>RNA</t> (si RNA ) on blood‐brain barrier integrity at 24 hours after subarachnoid hemorrhage ( SAH ). NTN ‐1 si RNA aggravated neurological deficits (A) and increased brain water content (B) and Evans blue ( EB ) extravasation (C) in both hemispheres. n=6 for each group. D, Representative fluorescent micrograph of EB extravasation and quantitative analyses of the intensity of EB fluorescence in the ipsilateral cortex. n=2 for each group. * P <0.05 vs sham, # P <0.05 vs Vehicle, & P <0.05 vs NTN ‐1 and Scr si RNA ; @ P <0.05 vs NTN ‐1. LH indicates left hemisphere; RH , right hemisphere; Scr si RNA , scramble si RNA . Scale bar=25 μm.
Dcc Sirnas, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dcc+sirnas/DCC+siRNA/pmc04734837-97-2-16
Average 90 stars, based on 1 article reviews
dcc sirnas - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
human dcc targeting sirna  (Ribobio co)
90
Ribobio co human dcc targeting sirna
The effects of silencing of endogenous Netrin‐1 ( NTN ‐1) by NTN ‐1 <t>small</t> <t>interfering</t> <t>RNA</t> (si RNA ) on blood‐brain barrier integrity at 24 hours after subarachnoid hemorrhage ( SAH ). NTN ‐1 si RNA aggravated neurological deficits (A) and increased brain water content (B) and Evans blue ( EB ) extravasation (C) in both hemispheres. n=6 for each group. D, Representative fluorescent micrograph of EB extravasation and quantitative analyses of the intensity of EB fluorescence in the ipsilateral cortex. n=2 for each group. * P <0.05 vs sham, # P <0.05 vs Vehicle, & P <0.05 vs NTN ‐1 and Scr si RNA ; @ P <0.05 vs NTN ‐1. LH indicates left hemisphere; RH , right hemisphere; Scr si RNA , scramble si RNA . Scale bar=25 μm.
Human Dcc Targeting Sirna, supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dcc+sirnas/human+dcc+targeting+sirna/pm35871235-69-19-28
Average 90 stars, based on 1 article reviews
human dcc targeting sirna - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
cholesterol-modified dcc sirna  (Ribobio co)
90
Ribobio co cholesterol-modified dcc sirna
The effects of silencing of endogenous Netrin‐1 ( NTN ‐1) by NTN ‐1 <t>small</t> <t>interfering</t> <t>RNA</t> (si RNA ) on blood‐brain barrier integrity at 24 hours after subarachnoid hemorrhage ( SAH ). NTN ‐1 si RNA aggravated neurological deficits (A) and increased brain water content (B) and Evans blue ( EB ) extravasation (C) in both hemispheres. n=6 for each group. D, Representative fluorescent micrograph of EB extravasation and quantitative analyses of the intensity of EB fluorescence in the ipsilateral cortex. n=2 for each group. * P <0.05 vs sham, # P <0.05 vs Vehicle, & P <0.05 vs NTN ‐1 and Scr si RNA ; @ P <0.05 vs NTN ‐1. LH indicates left hemisphere; RH , right hemisphere; Scr si RNA , scramble si RNA . Scale bar=25 μm.
Cholesterol Modified Dcc Sirna, supplied by Ribobio co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dcc+sirnas/cholesterol+modified+dcc+sirna/pm37541362-53-1-10
Average 90 stars, based on 1 article reviews
cholesterol-modified dcc sirna - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
dcc mouse sirna oligo duplex  (OriGene)
N/A
Dcc Mouse 3 unique 27mer siRNA duplexes 2 nmol each
   Buy from Supplier
dcc human sirna oligo duplex  (OriGene)
N/A
DCC Human 3 unique 27mer siRNA duplexes 2 nmol each
   Buy from Supplier

Image Search Results


The effects of silencing of endogenous Netrin‐1 ( NTN ‐1) by NTN ‐1 small interfering RNA (si RNA ) on blood‐brain barrier integrity at 24 hours after subarachnoid hemorrhage ( SAH ). NTN ‐1 si RNA aggravated neurological deficits (A) and increased brain water content (B) and Evans blue ( EB ) extravasation (C) in both hemispheres. n=6 for each group. D, Representative fluorescent micrograph of EB extravasation and quantitative analyses of the intensity of EB fluorescence in the ipsilateral cortex. n=2 for each group. * P <0.05 vs sham, # P <0.05 vs Vehicle, & P <0.05 vs NTN ‐1 and Scr si RNA ; @ P <0.05 vs NTN ‐1. LH indicates left hemisphere; RH , right hemisphere; Scr si RNA , scramble si RNA . Scale bar=25 μm.

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Netrin‐1 Preserves Blood‐Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats

doi: 10.1161/JAHA.116.005198

Figure Lengend Snippet: The effects of silencing of endogenous Netrin‐1 ( NTN ‐1) by NTN ‐1 small interfering RNA (si RNA ) on blood‐brain barrier integrity at 24 hours after subarachnoid hemorrhage ( SAH ). NTN ‐1 si RNA aggravated neurological deficits (A) and increased brain water content (B) and Evans blue ( EB ) extravasation (C) in both hemispheres. n=6 for each group. D, Representative fluorescent micrograph of EB extravasation and quantitative analyses of the intensity of EB fluorescence in the ipsilateral cortex. n=2 for each group. * P <0.05 vs sham, # P <0.05 vs Vehicle, & P <0.05 vs NTN ‐1 and Scr si RNA ; @ P <0.05 vs NTN ‐1. LH indicates left hemisphere; RH , right hemisphere; Scr si RNA , scramble si RNA . Scale bar=25 μm.

Article Snippet: Following the manufacturer's instructions, rat NTN‐1 siRNA (Thermo Fisher Scientific, Waltham, MA), DCC siRNA (OriGene Technologies, Rockville, MD), or negative control scramble siRNA (OriGene Technologies) was dissolved in transfection reagent (OriGene Technologies).

Techniques: Small Interfering RNA, Fluorescence

Changes in expressions of downstream signaling pathway of Focal Adhesion Kinase ( FAK )/RhoA after exogenous Netrin‐1 ( NTN ‐1) treatment and NTN ‐1 si RNA pretreatment at 24 hours post–subarachnoid hemorrhage ( SAH ). Exogenous NTN ‐1 significantly further enhanced the FAK phosphorylation (A), which resulted in the suppression of RhoA activity (B). While the endogenous NTN ‐1 was depleted by use of NTN ‐1 si RNA , the p‐ FAK level decreased (A), which augmented the RhoA activation (B). The RhoA activity was negatively related to the levels of endothelial tight junction proteins including ZO ‐1 (C) and Occludin (D) in the ipsilateral hemisphere. Relative densities of each protein have been normalized against the sham group. n=6 for each group. * P <0.05 vs sham, # P <0.05 vs vehicle, and & P <0.05 vs NTN ‐1 and Scr si RNA . Scr si RNA indicates scramble si RNA ; siRNA, small interfering RNA.

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Netrin‐1 Preserves Blood‐Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats

doi: 10.1161/JAHA.116.005198

Figure Lengend Snippet: Changes in expressions of downstream signaling pathway of Focal Adhesion Kinase ( FAK )/RhoA after exogenous Netrin‐1 ( NTN ‐1) treatment and NTN ‐1 si RNA pretreatment at 24 hours post–subarachnoid hemorrhage ( SAH ). Exogenous NTN ‐1 significantly further enhanced the FAK phosphorylation (A), which resulted in the suppression of RhoA activity (B). While the endogenous NTN ‐1 was depleted by use of NTN ‐1 si RNA , the p‐ FAK level decreased (A), which augmented the RhoA activation (B). The RhoA activity was negatively related to the levels of endothelial tight junction proteins including ZO ‐1 (C) and Occludin (D) in the ipsilateral hemisphere. Relative densities of each protein have been normalized against the sham group. n=6 for each group. * P <0.05 vs sham, # P <0.05 vs vehicle, and & P <0.05 vs NTN ‐1 and Scr si RNA . Scr si RNA indicates scramble si RNA ; siRNA, small interfering RNA.

Article Snippet: Following the manufacturer's instructions, rat NTN‐1 siRNA (Thermo Fisher Scientific, Waltham, MA), DCC siRNA (OriGene Technologies, Rockville, MD), or negative control scramble siRNA (OriGene Technologies) was dissolved in transfection reagent (OriGene Technologies).

Techniques: Phospho-proteomics, Activity Assay, Activation Assay, Small Interfering RNA